Symptoms of Primary Ocular Lymphoma (Lymphoma of the Eye)

Lymphomas can arise from most any lymphatic tissue (lymph nodes, spleen, thymus, mucosa associated lymphoid tissue (MALT). The eye is a fairly rare place to get lymphoma but it does happen. The medical term for this is an Extranodal Lymphoma as it arises outside the lymph nodes.

Non Hodgkin's lymphoma can start in the eye. It is called ocular lymphoma when it did not start elsewhere including the central nervous system (CNS) (brain etc.) These lymphomas are all quite rare. Isolated ocular lymphoma apparently is increasing in frequency, maybe due to occurrence in some AIDS patients. It represents a difficult extranodal site to treat.

Lymphoma Treatment Center

Insurance Accepted.
Innovative Lymphoma Treatments.
Call 415-343-6162 Today

Ocular lymphomas should not be confused with other cancers that can might strike the eye or related tissue or spread to the eye from another location.

Symptoms

The most common presenting ocular symptoms are blurred vision and floaters. Pain and conjunctival hyperemia (engorgement of blood vessels around the eye) are rare. Vision is often decreased. Biomicroscopic exam often shows mild anterior segment inflammation with cells and flare and keratic precipitates. Vitreous cells occurring in sheets are characteristic. Although the disease may begin with one eye, bilateral (both eye) involvement is common after several months.

Doctors may look for Interleukin-10, a growth and differentiation factor for B lymphocytes to determine if the condition is lymphoma instead of another eye condition which may be attracting lymphocytes such as an infection. A recent 2004 study suggests that CDR3 polymorphism analysis is recommended to confirm clonality.

Treatment

The disease treatment may include external beam radiation, chemotherapy, or both.

Radioimmunotherapy regimens such as Zevalin show promising results in clinical trials for many types of B-cell NHLs.

Photo: Pexels

Lymphoma Treatment Center

Insurance Accepted.
Innovative Lymphoma Treatments.
Call 415-343-6162 Today

More Articles

More Articles

This entry looks at Non Hodgkin's Lymphoma in the lungs, clinically known as pulmonary lymphoma, one of the subtypes of lymphoma. 'Lymphoma' is an...

In order to prevent developing any subtype of lymphoma, it would be helpful to know the causes of lymphoma. Unfortunately, in virtually every case...

BEAM chemotherapy is an acronym representing a small family of combination chemotherapy regimens that are used chiefly as salvage regimens in the...

There are two types of cancer: benign and malignant. Benign cancers are the kind that don't spread and don't threaten one's life. Malignant...

The Erythrocyte Sedimentation Rate (ESR - sometimes called sed rate or sedimentation rate) is a nonspecific screening test for various...

Blood counts can be used to identify disease and monitor patient health during cancer treatments. Though these tests cannot diagnose lymphoma on...

MALT lymphoma is a rare B-cell non-Hodgkin's lymphoma that typically runs an indolent or slow-growing clinical...

Mantle cell lymphoma (MCL) is just one of 50-60 known B-cell subtypes of...

After some of the dust has settled, the thoughts of many new lymphoma patients turn to diet and nutrition. They want to know if, in the past,...

According to a study by Japanese researchers, the SMILE combination chemotherapy protocol is effective against extranodal natural killer/T-cell...

In a perfect world, every case of cancer would respond to, and be cured by first-line therapy. Unfortunately, it is not often the case. This is...

Patients treated with maintenance rituximab had three times longer progression-free survival. This is a summary of an article published in the...

Prednisone is a glucocorticosteroid (a steroid) used in the treatment of many types of cancers. It functions as an anti-inflammatory medicine that...

In 1964, researchers at the National Cancer Institute developed the first combination chemotherapy that cured a...

Since so many chemotherapy agents can affect a patient’s sex drive and fertility, thinking about these issues prior...