Bone Marrow Transplant Cures Child with Leukemia of Peanut Allergy

While it was previously known that a bone marrow transplant (BMT) can confer the donor's peanut allergy onto the recipient, a case has been found in which the recipient was cured of peanut allergy following a BMT.

According to research presented at the American College of Allergy, Asthma and Immunology annual meeting, a 10-year-old patient with acute lymphocytic leukemia (ALL) was found to be cured of his peanut allergy after undergoing an allogenic bone marrow transplant.

Transplant leads to allergy cure

Lead study author Yong Luo, M.D., Ph.D. said that the child had been diagnosed with a peanut allergy at age 15 months, following a severe reaction to peanuts involving hives and vomiting.

At age 10, he was treated for ALL by a bone marrow transplant from a donor without any known allergies, and he appeared to be cured of the allergy.

The cure was confirmed by allergists, who conducted what's known as an oral food challenge, a test carried out under strong medical scrutiny because it involves peanut ingestion. The child in question showed no signs of allergy from the test.

While researchers could offer no immediate explanation for the cure, it was noted by study co-author Steven Weiss, M.D., Ph.D., that the case boosts the evidence indicating that "genetic modification during the early stages of immune cell development in bone marrow may play a large role in causing allergy."

Source: MNT

More Articles

More Articles

Mantle cell lymphoma (MCL) is a rare type of B-Cell lymphoma. It presents itself in the mantle zone of lymph nodes...

Large Cell Lymphoma (LCL) is typically an aggressive (fast growing) cancer of either the B cell or T cell type. They are one of the most common...

Indolent Lymphoma, or Indolent Non-Hodgkin’s Lymphomas (NHLs), are slow growing, low-grade cancers (as opposed to ...

A lymphoma prognosis varies greatly depending on the type of lymphoma. There are more than 35 types of lymphoma, including 5 types of...

Lymphomas are classified based on the type of cells involved. Non-Hodgkin’s lymphomas are marked by mutations of...

Hodgkin's Lymphoma (Disease) has a colorful history: It was not the first cancer discovered but it was one of the first in which treatments were...

There are two types of cancer: benign and malignant. Benign cancers are the kind that don't spread and don't threaten one's life. Malignant...

Cancer bracelets are undeniably popular, and if purchased through reliable sources such as major charities, they help contribute to the fight...

Hodgkin's Disease—also referred to as Hodgkin's Lymphoma, these are the exact same diseases, just...

Lymphoma is a cancer of the b- and t-cell lymphocytes, part of the immune system. They account for the most frequent head and neck malignancies....

Lymphoma is a cancer of the lymphatic system, causing B-cell or...

Lymphoma is a cancer affecting the white blood cells (lymphocytes) of the body's immune system. The cells begin to grow abnormally and much faster...

As a kind of cancer, lymphoma attacks the lymphocytes and lymph nodes that are part of the immune system. Head and neck lymphoma results when...

Some cancers have clear environmental causes. Oral cancer is strongly tied to the use of chewing tobacco, and lung cancer is well-known to be much...

The Follicular Lymphoma International Prognostic Index, or FLIPI, is a standardized guide to help oncological diagnosticians accurately calculate...