New Effective Lymphoma Treatment Approved by FDA

Approval for an investigational drug to treat Hodgkin’s lymphoma in patients who have already had a stem cell transplant was unanimously approved on Thursday by an FDA advisory panel.

As per the details of the arrangement, the drug will be utilized for patients with relapsed or resistant systematic anaplastic large cell lymphoma.

An FDA advisory panel voted unanimously Thursday to recommend accelerated approval for an investigational drug to treat Hodgkin lymphoma in patients who have already had a stem cell transplant, and for patients with relapsed or resistant systemic anaplastic large cell lymphoma. Brentuximab vedotin, which Seattle Genetics has already said it will market as Adcetris, is the combination of antibody and chemotherapy drug to effectively treat rare blood cancer. While the antibody binds the CD30-positive Reed-Sternberg cells, the monomethyl auristatin attacks the internal structure of the cells.

The FDA panel in question, the Oncologic Drugs Advisory Committee, voted it through with a 10-0 total. Much of the approval was based on the very successful trial that the company presented, during which three-quarters of the patients treated had at least a mild reduction in tumor burden while more than a third had an entire remission.

Considering the fact that no new agents have been approved for the treatment of Hodgkin’s lymphoma since the late 1970s, this could be a potentially monumental first step on the road to getting a proper lymphoma treatment on the market.

More Articles

More Articles

Lymphoma patients may have the option to participate in clinical trials, gaining access to an experimental treatment before it is widely available...

Since there are several subtypes of T cell lymphoma, there will necessarily be several non-specific T cell lymphoma...

In order to prevent developing any subtype of lymphoma, it would be helpful to know the causes of lymphoma. Unfortunately, in virtually every case...

After surviving lymphoma treatments, patients should be on the lookout for late effects. These are symptoms that arise well after treatment has...

Canine lymphoma is a fairly common cancer in American dogs. The most commonly seen lymphoma in America is a type called Lymphosarcoma, although...

Advances in the treatment of Hodgkin's lymphoma have resulted in remarkable survival rates, even for...

Since so many chemotherapy agents can affect a patient’s sex drive and fertility, thinking about these issues prior...

The short answer: both. Let's begin with a simple definition of radiation: Radiation is the energy emitted from an energy source. That energy...

According to a study by Japanese researchers, the SMILE combination chemotherapy protocol is effective against extranodal natural killer/T-cell...

Patients treated with maintenance rituximab had three times longer progression-free survival. This is a summary of an article published in the...

When you consider that the adult human body has anywhere from 300 to 700 lymph nodes, the better question might not be where ARE they located, but...

This entry looks at a non-Hodgkin's lymphoma called true histiocytic lymphoma (THL), also referred to as diffuse histiocytic lymphoma, and...

Lymphomatous meningitis [LM], also known as leukemic meningitis, is an extremely serious peripheral cancer that attacks the tissue that covers the...

Hodgkin's Disease—also referred to as Hodgkin's Lymphoma, these are the exact same diseases, just...

Intravascular lymphoma is a subtype of 'Lymphoma', an umbrella term that loosely refers to several dozen...