Canine Cancer Research

If you know of a dog with cancer like lymphoma or others, this research study could help doctors better understand what causes cancer in dogs.



Breeds: Akita, American Cocker Spaniel, Boxer, Bullmastiff, Chinese Shar-Pei, Chow Chow, English Cocker Spaniel, English Springer Spaniel, Flat-Coated Retriever, German Shepherd, Giant Schnauzer, Golden Retriever,
Greyhound, Labrador Retriever, Leonberger, Mastiff, Miniature Poodle, Miniature Schnauzer, Pointer, Pug, Rottweiler, Scottish Terrier, Standard Poodle, Standard Schnauzer, Toy Poodle



After completing the dog genome sequencing project, the Broad Institute of Harvard and MIT and collaborators are now working on identifying disease genes predisposing dogs to cancer. Identification of such genes could lead to carrier testing, a better understanding of the disease and long term better treatments for the disease in both dogs and humans. More information can be found at: www.broad.mit.edu/mammals/dog. For each of the below diseases researchers need blood samples from affected dogs as well as blood samples from healthy older (>6 year old) dogs.



Lymphoma
PI: Kerstin Lindblad-Toh Broad

Focus: Golden Retrievers, Boxers

Additional breeds included: Cocker Spaniel, Rottweiler, Akita, Flat-Coated Retriever

Please contact: Dog-info@broad.mit.edu



Mammary tumors
PI: Kerstin Lindblad-Toh Broad and Elizabeth McNiel, U. Minnesota

Focus: English Springer Spaniel

Additional breeds included: German Shepherds, Cocker Spaniels and Boxers

Please contact: Dog-info@broad.mit.edu



Melanoma
PI: Kerstin Lindblad-Toh Broad and Phil Bergman, Animal Medical Center, NY

Breeds included: ALL including Scottish Terriers, Cocker Spaniels, Black Labrador Retrievers, Rottweilers, Chow Chows, and Pugs

Please contact: Dog-info@broad.mit.edu



Mast cell tumors
Collaborators: Kerstin Lindblad-Toh Broad and Cheryl London, UC Davis

Focus: Pugs and Chinese Shar-Pei

Additional breeds included: Pit Bull Terrier, Labrador Retriever, Golden Retriever, German Shepherd, Cocker Spaniel, Boxer

Please contact: Dog-info@broad.mit.edu



Researchers at the AMC Cancer Research Center and University of Colorado Health Science Center are looking for samples for the following projects:



Lymphoma
Researchers need samples from any dog that has an AKC registration number. Eligible dogs will undergo standard of care treatment and provide blood samples as well. Availability of 2 or more unaffected relatives that are >6
years old is desirable. They also would encourage people who have dogs that re related to study subjects that are affected to participate. Owners of all dogs will be asked to fill out a follow-up questionnaire.

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