Primary B Cell Cutaneous Lymphoma

This entry looks at primary B cell cutaneous lymphoma, one of the subtypes of lymphoma. 'Lymphoma' is an umbrella term that loosely refers to several dozen independent categorical types and subtypes of cancers of the lymphatic system.

B Cell Cutaneous Lymphoma

A cutaneous lymphoma refers to several subtypes of lymphoma that affect the skin. These subtypes include:

And of course there are a few more, including primary B cell cutaneous lymphoma, in which B cell lymphocytes in the skin become cancerous.

B Cell Cutaneous Lymphoma

Primary B cell cutaneous lymphoma is a non-Hodgkin's lymphoma the origin of which is in the skin (thus the term 'primary'). If the disease spread to the skin from a different primary site, it would be considered secondary B cell cutaneous lymphoma and therefore a systemic disease. This however is extremely rare; it is exceedingly more common for primary B cell cutaneous lymphoma.

There are a handful of subtypes of primary B cell cutaneous lymphoma. They are:

  • Primary cutaneous follicle center cell lymphoma (indolent)
  • Primary cutaneous marginal zone B cell lymphoma (indolent)
  • Large B-cell lymphoma of the leg (intermediately aggressive)

B Cell Cutaneous Lymphoma Treatment

Initial treatment for lower-stage primary B cell cutaneous lymphoma will involve at least one or more of the following therapuetic options:

  • Locoregional radiotherapy
  • Excision (surgical removal)
  • Observation (only for certain cases)
  • Topical applications

B Cell Cutaneous Lymphoma Prognosis

In general, primary B cell cutaneous lymphoma has an excellent prognosis, with a high cure rate (around 90%) when the appropriate treatment option is used. Although prognosis is very good, recurrence is not uncommon.

Sources

More Articles

More Articles

Lymphoma patients may have the option to participate in clinical trials, gaining access to an experimental treatment before it is widely available...

Since there are several subtypes of T cell lymphoma, there will necessarily be several non-specific T cell lymphoma...

In order to prevent developing any subtype of lymphoma, it would be helpful to know the causes of lymphoma. Unfortunately, in virtually every case...

After surviving lymphoma treatments, patients should be on the lookout for late effects. These are symptoms that arise well after treatment has...

Canine lymphoma is a fairly common cancer in American dogs. The most commonly seen lymphoma in America is a type called Lymphosarcoma, although...

Advances in the treatment of Hodgkin's lymphoma have resulted in remarkable survival rates, even for...

Since so many chemotherapy agents can affect a patient’s sex drive and fertility, thinking about these issues prior...

The short answer: both. Let's begin with a simple definition of radiation: Radiation is the energy emitted from an energy source. That energy...

According to a study by Japanese researchers, the SMILE combination chemotherapy protocol is effective against extranodal natural killer/T-cell...

Patients treated with maintenance rituximab had three times longer progression-free survival. This is a summary of an article published in the...

When you consider that the adult human body has anywhere from 300 to 700 lymph nodes, the better question might not be where ARE they located, but...

This entry looks at a non-Hodgkin's lymphoma called true histiocytic lymphoma (THL), also referred to as diffuse histiocytic lymphoma, and...

Lymphomatous meningitis [LM], also known as leukemic meningitis, is an extremely serious peripheral cancer that attacks the tissue that covers the...

Hodgkin's Disease—also referred to as Hodgkin's Lymphoma, these are the exact same diseases, just...

Intravascular lymphoma is a subtype of 'Lymphoma', an umbrella term that loosely refers to several dozen...