Primary B Cell Cutaneous Lymphoma

This entry looks at primary B cell cutaneous lymphoma, one of the subtypes of lymphoma. 'Lymphoma' is an umbrella term that loosely refers to several dozen independent categorical types and subtypes of cancers of the lymphatic system.

B Cell Cutaneous Lymphoma

A cutaneous lymphoma refers to several subtypes of lymphoma that affect the skin. These subtypes include:

And of course there are a few more, including primary B cell cutaneous lymphoma, in which B cell lymphocytes in the skin become cancerous.

B Cell Cutaneous Lymphoma

Primary B cell cutaneous lymphoma is a non-Hodgkin's lymphoma the origin of which is in the skin (thus the term 'primary'). If the disease spread to the skin from a different primary site, it would be considered secondary B cell cutaneous lymphoma and therefore a systemic disease. This however is extremely rare; it is exceedingly more common for primary B cell cutaneous lymphoma.

There are a handful of subtypes of primary B cell cutaneous lymphoma. They are:

  • Primary cutaneous follicle center cell lymphoma (indolent)
  • Primary cutaneous marginal zone B cell lymphoma (indolent)
  • Large B-cell lymphoma of the leg (intermediately aggressive)

B Cell Cutaneous Lymphoma Treatment

Initial treatment for lower-stage primary B cell cutaneous lymphoma will involve at least one or more of the following therapuetic options:

  • Locoregional radiotherapy
  • Excision (surgical removal)
  • Observation (only for certain cases)
  • Topical applications

B Cell Cutaneous Lymphoma Prognosis

In general, primary B cell cutaneous lymphoma has an excellent prognosis, with a high cure rate (around 90%) when the appropriate treatment option is used. Although prognosis is very good, recurrence is not uncommon.

Sources

More Articles

More Articles

According to a study by Japanese researchers, the SMILE combination chemotherapy protocol is effective against extranodal natural killer/T-cell...

Patients treated with maintenance rituximab had three times longer progression-free survival. This is a summary of an article published in the...

When you consider that the adult human body has anywhere from 300 to 700 lymph nodes, the better question might not be where ARE they located, but...

This entry looks at a non-Hodgkin's lymphoma called true histiocytic lymphoma (THL), also referred to as diffuse histiocytic lymphoma, and...

Lymphomatous meningitis [LM], also known as leukemic meningitis, is an extremely serious peripheral cancer that attacks the tissue that covers the...

Hodgkin's Disease—also referred to as Hodgkin's Lymphoma, these are the exact same diseases, just...

Intravascular lymphoma is a subtype of 'Lymphoma', an umbrella term that loosely refers to several dozen...

While the average lifespan for hamsters is only about 2.5 years, and they are therefore less prone to long-term illnesses, it is possible for a...

Burkitt's lymphoma is an aggressive B-cell lymphoma that is common in children...

Lymphoma is a cancer of the lymphatic system, causing B-cell or...

The term NK T cell lymphoma refers to one of two subtypes of lymphoma that affect the NK (Natural Killer)...

Lymphoma is a life-threatening disease, but is very treatable in most cases. The 5-year survival for patients diagnosed with non-Hodgkin's...

T cell lymphoma treatment options for these cancers are not especially effective and there is no absolute consensus about optimal treatments for...

Marginal zone lymphomas (MZL) are indolent lymphomas that affect the B-cells. The...

Lymphomas can arise from most any lymphatic tissue (lymph nodes, spleen, thymus, mucosa associated lymphoid...