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Lymphoma Information Network » Lymphoma Info » Anti-nausea: Zofran / Ondansetron

Anti-nausea: Zofran / Ondansetron

odansetron molecule
Odansetron molecule

Generic Name: ondansetron

Zofran is an anti-nausea drug administered to many chemotherapy and radiation patients while they undergo treatment.

Nausea occurs when your body produces a signaling chemical called serotonin to induce nausea in response to treatment. This signal binds to a receptor in your body, which triggers the nausea. Zofran works by blocking the serotonin receptor, thus preventing the response.

Drug Administration

Zofran can be administered intravenously (IV) or orally in pill form. If taken as a pill, you should not double dose, even if you miss one pill. Take only as directed.

Side Effects

Most side effects are mild, but Zofran can impair your thinking and reaction time, so you shouldn’t drive while taking it. These side effects include blurred vision, anxiety, and fainting.

Other symptoms include a slowed heart rate, headaches, dry mouth, shivering, frequent urination, trouble breathing, and allergic reactions. Alert your doctor to any drug allergies you have.

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SupportGroups.com aims to build awareness and provide support for Hodgkin's Lymphoma and Non-Hodgkin's Lymphoma. If you are a friend or parent of a person that has been diagnosed with Lymphoma, or you have been diagnosed with Lymphoma, you are not alone. Share personal experiences, evaluate information and get support during times of need, illness, treatment or recovery.

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Since the early 1970s, incidence rates for non-Hodgkin’s lymphoma have nearly doubled. Incidence rates for Hodgkin’s disease have declined about 60%. Better means of diagnosis has also increased the number as doctors better understand cancer of lymphocytes verses other diseases.