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Chemotherapy - Mustargen

mustargen molecule
Mechlorethamine molecule

Generic Name: Mechlorethamine

Other Names: Nitrogen Mustard, Mustine

Mustargen is a chemotherapy drug that is administered for the treatment of lung cancer, breast cancer, and lymphomas. It functions as an alkylating agent, meaning it interferes with DNA reproduction and cell replication.

The drug is usually administered for the treatment of Hodgkin’s Lymphoma and Cutaneous T-Cell Lymphoma, a Non-Hodgkin’s Lymphoma. It is commonly used in conjunction with other chemotherapy drugs in the following regimens:

Drug Administration

For the treatment of Hodgkin’s Disease, it is administered via an IV drip. The drug should only be injected into a vein, not an artery, as it can cause irritation. If redness or swelling occurs at the injection site, notify a doctor immediately.

For the treatment of Cutaneous T-Cell Lymphoma, it is applied as a topical cream to the skin to help with skin lesions.

Need Help with Treatment Decisions? Click here to sign up for the free Profiler Treatment Option Tool. This tool will assist you in understanding your treatment options and possible side effects.

Side Effects

Common side effects include vomiting, low blood counts, mouth sores, hair loss, and infertility. If the drug is used topically, then redness or dryness of the skin can occur.

Less common side effects include loss of appetite, tinnitus (ringing in the ears), taste changes, fever, and diarrhea. In some cases, patients may develop a secondary cancer, such as leukemia.

Cancer Support Groups

SupportGroups.com aims to build awareness and provide support for Hodgkin's Lymphoma and Non-Hodgkin's Lymphoma. If you are a friend or parent of a person that has been diagnosed with Lymphoma, or you have been diagnosed with Lymphoma, you are not alone. Share personal experiences, evaluate information and get support during times of need, illness, treatment or recovery.

For more information on Hodgkin's Disease, please see the following pages:

For more information on Non-Hodgkin Lymphoma, please see the following pages:

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SupportGroups.com aims to build awareness and provide support for Hodgkin's Lymphoma and Non-Hodgkin's Lymphoma. If you are a friend or parent of a person that has been diagnosed with Lymphoma, or you have been diagnosed with Lymphoma, you are not alone. Share personal experiences, evaluate information and get support during times of need, illness, treatment or recovery.

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Did You Know?
Since the early 1970s, incidence rates for non-Hodgkin’s lymphoma have nearly doubled. Incidence rates for Hodgkin’s disease have declined about 60%. Better means of diagnosis has also increased the number as doctors better understand cancer of lymphocytes verses other diseases.
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