Chemotherapy - Mustargen

Generic Name: Mechlorethamine

Other Names: Nitrogen Mustard, Mustine

Mustargen is a chemotherapy drug that is administered for the treatment of lung cancer, breast cancer, and lymphomas. It functions as an alkylating agent, meaning it interferes with DNA reproduction and cell replication.

The drug is usually administered for the treatment of Hodgkin’s Lymphoma and Cutaneous T-Cell Lymphoma, a Non-Hodgkin’s Lymphoma. It is commonly used in conjunction with other chemotherapy drugs in the following regimens:

Drug Administration

For the treatment of Hodgkin’s Disease, it is administered via an IV drip. The drug should only be injected into a vein, not an artery, as it can cause irritation. If redness or swelling occurs at the injection site, notify a doctor immediately.

For the treatment of Cutaneous T-Cell Lymphoma, it is applied as a topical cream to the skin to help with skin lesions.

Side Effects

Common side effects include vomiting, low blood counts, mouth sores, hair loss, and infertility. If the drug is used topically, then redness or dryness of the skin can occur.

Less common side effects include loss of appetite, tinnitus (ringing in the ears), taste changes, fever, and diarrhea. In some cases, patients may develop a secondary cancer, such as leukemia.

For more information on Hodgkin's Disease, please see the following pages:

For more information on Non-Hodgkin Lymphoma, please see the following pages:

More Articles

More Articles

Lymphoma patients may have the option to participate in clinical trials, gaining access to an experimental treatment before it is widely available...

Since there are several subtypes of T cell lymphoma, there will necessarily be several non-specific T cell lymphoma...

In order to prevent developing any subtype of lymphoma, it would be helpful to know the causes of lymphoma. Unfortunately, in virtually every case...

After surviving lymphoma treatments, patients should be on the lookout for late effects. These are symptoms that arise well after treatment has...

Canine lymphoma is a fairly common cancer in American dogs. The most commonly seen lymphoma in America is a type called Lymphosarcoma, although...

Advances in the treatment of Hodgkin's lymphoma have resulted in remarkable survival rates, even for...

Since so many chemotherapy agents can affect a patient’s sex drive and fertility, thinking about these issues prior...

The short answer: both. Let's begin with a simple definition of radiation: Radiation is the energy emitted from an energy source. That energy...

According to a study by Japanese researchers, the SMILE combination chemotherapy protocol is effective against extranodal natural killer/T-cell...

Patients treated with maintenance rituximab had three times longer progression-free survival. This is a summary of an article published in the...

When you consider that the adult human body has anywhere from 300 to 700 lymph nodes, the better question might not be where ARE they located, but...

This entry looks at a non-Hodgkin's lymphoma called true histiocytic lymphoma (THL), also referred to as diffuse histiocytic lymphoma, and...

Lymphomatous meningitis [LM], also known as leukemic meningitis, is an extremely serious peripheral cancer that attacks the tissue that covers the...

Hodgkin's Disease—also referred to as Hodgkin's Lymphoma, these are the exact same diseases, just...

Intravascular lymphoma is a subtype of 'Lymphoma', an umbrella term that loosely refers to several dozen...