Lymphoma Information Network - Dacarbazine / DTIC

Lymphoma Information Network - Hodgkin's Disease and the Non-Hodgkin's Lymphomas

Site Navigation		Chemotherapy - Dacarbazine

Dacarbazine (common brand names DTIC, DTIC-Dome) is a chemotherapy agent used in the treatment of Hodgkin's Disease. It is more often than not given in conjunction with other chemotherapy agents in a multidrug regimen such as ABVD. An alkylating agent, it functions as a methylating agent after metabolic activation in the liver. Dacarbazine is also used to treat melanoma, a cancer of the skin.

Before taking this medicine: Inform your doctor if you have allergies, are pregnant or plan to have children, are breast feeding, taking other medications including those over the counter, have any other medical problems, have ever been treated with radiation or for cancer.

While taking this medicine: Keep in touch with your doctor regularly. Do not get any vaccinations without checking with your doctor.

Short Term Side Effects: Common: Redness, pain, or swelling at the site of injection, nausea, vomiting. Less Common: black stools, blood in urine or stool, cough, fever/chills, lower back/side pain, painful or difficult urination, pinpoint red spots on skin, sores in mouth and on lips.

Long Term Side Effects: Some hair loss which should return after treatment, transient (shorter term) reduction in liver and kidney function.

Regimens using Dacarbazine:

ABVD (Hodgkin's Disease - the "D")

Dacarbazine Reference Links:

Manufacturer's Information from Bayer (PDF format,
Adobe Acrobat reader / plug-in required)
Information on dacarbazine from Healthtouch (US)
Information sheet from CanCareSA (Australia)
Information on Alkalating Agents including dacarbazine from UNMC (bottom of page)

Manufacturer:

Ben Venue Laboratories, Inc
A division of Boehringer Ingelheim Pharmaceuticals Inc.
300 Northfield Road Bedford, OH 44146 USA

Distributors:

Miles Pharmaceutical, Inc. / Bayer Pharmaceutical
Customer Information: 800-998-9180
Address: 400 Morgan Lane West Haven, CT 06516

Disclaimer: This information is general in nature. Please consult with a doctor or the literature provided with the drug packaging if you need specific information on a drug. The author is not responsible for missing or inaccurate information and the reader assumes full responsibility for their actions. As always, please consult with medical personnel before undertaking any medical treatment.

For more information on Hodgkin's Disease, please see the following pages: :

Childhood Hodgkin's Disease: Chemotherapy

Childhood Hodgkin's Disease: Treatment

Childhood Hodgkin's Disease: Introduction

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The Lymphoma Information Network

This page is a work in progress - if you have more complete information, references, or other information please contact the author. The author is not in the medical field and does not warrant the correctness of the material on this page or the sites linked - please take online information and consult with your own medical team to make informed decisions.

Chemotherapy - Dacarbazine