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Marginal Zone Lymphomas
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Marginal zone lymphoma, lymph node
from Univ. Tokushima
from Univ. Tokushima
Marginal zone lymphomas (MZL) are indolent lymphomas that affect the B-cells. The marginal zone is the area in the B-cell in which the mutation occurs in this type of cancer. MZLs represent 2-4% of all NHL cases.
Nodal marginal zone lymphomas involved the lymph nodes directly. Extranodal marginal zone lymphomas involve only organs outside of the lymphatic system, such as the thyroid, GI tract, or skin. These extranodal cancers are also called mucosa-associated lymphatic tissue lymphomas lymphomas, or MALT lymphomas.
Splenic marginal zone lymphomas are considered a class of their own.
Treatment
Treatment varies depending on the type of disease and stage. Radioimmunotherapy treatments such as the Zevalin regimen, though not yet approved for mainstream use, show promising results as MZL therapy. Patients who are looking for more advanced treatment or who have lymphoma that does not respond to standard treatment may want to consider a clinical study. Click here to find clinical trials in your area.
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Related Articles
Non-Hodgkin's Lymphoma Information Pages:
- Non-Hodgkin's Lymphomas
- Non-Hodgkin's Lymphoma: Diagnosis
- Non-Hodgkin's Lymphoma: Aggressive Lymphomas
- Non-Hodgkin's Lymphoma: Indolent Lymphomas
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Other Pages of Interest:
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For nearly 30 years, Cancer Treatment Centers of America has been dedicated to finding the right combination of personalized cancer treatments for their patients. Call (877) 399-6937 or click here to learn more about treatment options.
Support Groups
For individuals, friends and families who are looking to connect during life's challenging times. Share personal experiences, evaluate information and get support during times of need, illness, treatment or recovery.
Find a Treatment Facility Near You
Click on a state below to find Lymphoma treatment options that could be right for you.
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