Marginal zone lymphomas (MZL) are indolent B-cell lymphomas. When marginal zone lymphomas involve the lymph nodes they are called nodal marginal zone B-cell lymphomas whereas when they involve places outside the lymph nodes (gastrointestinal tract, thyroid, breast, or skin) they are called mucosa-associated lymphatic tissue lymphomas (MALT or MALToma). Splenic (in the spleen) Marginal zone lymphomas are considered a third separate type. Together they represent less than 20% of all lymphomas.
Under the new WHO Lymphoma Classification System (2001), all three types of Marginal Zone Lymphoma are considered distinct entities and may be treated and studied separately.
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Resources
Hematopathology - Dr. David Weissman
Marginal Zone Lymphomas – Lymphomation
Related Articles
MALT lymphomas
Splenic Marginal Zone Lymphoma
Nodal Marginal Zone Lymphoma
Non-Hodgkin's Lymphoma Information Pages:
Non-Hodgkin's Lymphomas
Non-Hodgkin's Lymphoma: Diagnosis
Non-Hodgkin's Lymphoma: Aggressive Lymphomas
Non-Hodgkin's Lymphoma: Indolent Lymphomas
Non-Hodgkin's Lymphoma: Treatment
Non-Hodgkin's Lymphoma: Resources
Bone Marrow and Stem Cell Transplants
Other Pages of Interest:
Childhood Non-Hodgkin's Lymphoma Information
The Lymphoma Information Network
Books
Non-Hodgkin's Lymphomas, Peter M. Mauch (Editor), James O. Armitage (Editor), et al., 2004.
Section IV: Pathology, Biology, Clinical Evaluation, and Treatment Section
Chapter 22: Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue
Chapter 23: Nodal Marginal Zone B-Cell Lymphoma
Excellent but Technical:
An Illustrated Guide to Skin Lymphomas, Cerroni, Gatter, Kerl, 2nd. Ed, 2005
Chapter 10: Marginal Zone Lymphoma and Cutaneous Immunocytoma
