Treatment for Marginal Zone Lymphomas

Marginal zone lymphomas (MZL) are indolent lymphomas that affect the B-cells. The marginal zone is the area in the B-cell in which the mutation occurs in this type of cancer. MZLs represent 2-4% of all NHL cases.

Nodal marginal zone lymphomas involved the lymph nodes directly. Extranodal marginal zone lymphomas involve only organs outside of the lymphatic system, such as the thyroid, GI tract, or skin. These extranodal cancers are also called mucosa-associated lymphatic tissue lymphomas lymphomas, or MALT lymphomas.

Splenic marginal zone lymphomas are considered a class of their own.

Treatment

Treatment varies depending on the type of disease and stage. Radioimmunotherapy treatments such as the Zevalin regimen, though not yet approved for mainstream use, show promising results as MZL therapy.

Related Articles

Photo: Pexels

More Articles

More Articles

According to a study by Japanese researchers, the SMILE combination chemotherapy protocol is effective against extranodal natural killer/T-cell...

Patients treated with maintenance rituximab had three times longer progression-free survival. This is a summary of an article published in the...

When you consider that the adult human body has anywhere from 300 to 700 lymph nodes, the better question might not be where ARE they located, but...

This entry looks at a non-Hodgkin's lymphoma called true histiocytic lymphoma (THL), also referred to as diffuse histiocytic lymphoma, and...

Lymphomatous meningitis [LM], also known as leukemic meningitis, is an extremely serious peripheral cancer that attacks the tissue that covers the...

Hodgkin's Disease—also referred to as Hodgkin's Lymphoma, these are the exact same diseases, just...

Intravascular lymphoma is a subtype of 'Lymphoma', an umbrella term that loosely refers to several dozen...

While the average lifespan for hamsters is only about 2.5 years, and they are therefore less prone to long-term illnesses, it is possible for a...

Burkitt's lymphoma is an aggressive B-cell lymphoma that is common in children...

Lymphoma is a cancer of the lymphatic system, causing B-cell or...

The term NK T cell lymphoma refers to one of two subtypes of lymphoma that affect the NK (Natural Killer)...

Lymphoma is a life-threatening disease, but is very treatable in most cases. The 5-year survival for patients diagnosed with non-Hodgkin's...

T cell lymphoma treatment options for these cancers are not especially effective and there is no absolute consensus about optimal treatments for...

Lymphomas can arise from most any lymphatic tissue (lymph nodes, spleen, thymus, mucosa associated lymphoid...

Often the one who makes the first diagnosis of Hodgkin's Lymphoma / Disease is the person affected. There are some...