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Lymphoma Information Network » Lymphoma Info » Bone Marrow and Stem Cell Transplants to Treat Lymphoma

Bone Marrow and Stem Cell Transplants to Treat Lymphoma

Embryonic stem cells,
image by Nissim Benvenisty
The terms "Hodgkin's Disease," "Hodgkin's Lymphoma," and "Hodgkin Lymphoma" are used interchangeably throughout this site.

Bone Marrow Transplants (BMT) and Peripheral Blood Stem Cell Transplants (PBSCT) are emerging as mainstream treatment for many cancers, including Hodgkin's Disease and Medium/High grade (aggressive) Non-Hodgkin's lymphoma.

Bone Marrow Transplants with high-dose chemotherapy

BMTs have been used to treat lymphoma for more than 10 years, but until recently they were used mostly within clinical trials. Now BMTs are being used in conjunction with high doses of chemotherapy as a mainstream treatment.

When high doses of chemotherapy are planned, which can destroy the patient’s bone marrow, physicians will typically remove marrow from the patient’s bone before treatment and freeze it. After chemotherapy, the marrow is thawed and injected into a vein to replace destroyed marrow. This type of transplant is called an autologous transplant. If the transplanted marrow is from another person, it is called an allogeneic transplant.

Stem Cell Transplants: another option

In PBSCTs, another type of autologous transplant, the patient's blood is passed through a machine that removes the stem cells – the immature cells from which all blood cells develop. This procedure is called apheresis and usually takes three or four hours over one or more days. After treatment to kill any cancer cells, the stem cells are frozen until they are transplanted back to the patient. Studies have shown that PBSCTs result in shorter hospital stays and are safer and more cost effective than BMTs.

Clinical Trials and Other Options

Chemotherapy and Bone Marrow Transplants are one of many treatment options for Lymphoma. If you are looking for some assistance with treatment options, there is a free tool available to help you understand your treatment options and possible side effects. Click here to sign up for free.

Cancer Patients have more options through clinical studies. Follow this link to learn more and find a clinical study opportunity near you.

Radioimmunotherapy treatments such as Zevalin are very promising for certains NHL's and have now entered the mainstream of treatment options.

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Featured Treatment: Zevalin®

Zevalin® (Ibritumomab tiuxetan) is a form of radioimmunotherapy (a radiolabeled monoclonal antibody) for treatment of patients with relapsed or refractory, low‑grade or follicular B‑cell non‑Hodgkin's lymphoma (NHL). "Refractory" refers to a disease that does not respond to treatment.

Zevalin is the first radioummunotherapy treatment to be FDA-approved as a first-line therapy for lymphoma. Read more...

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SupportGroups.com aims to build awareness and provide support for Hodgkin's Lymphoma and Non-Hodgkin's Lymphoma. If you are a friend or parent of a person that has been diagnosed with Lymphoma, or you have been diagnosed with Lymphoma, you are not alone. Share personal experiences, evaluate information and get support during times of need, illness, treatment or recovery.

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Since the early 1970s, incidence rates for non-Hodgkin’s lymphoma have nearly doubled. Incidence rates for Hodgkin’s disease have declined about 60%. Better means of diagnosis has also increased the number as doctors better understand cancer of lymphocytes verses other diseases.
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