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Why Diversity in Clinical Trials Matter

As explained by Lynne Nguyen, the director of the Minority and Women Clinical Trials Recruitment Program at M. D. Anderson, “Clinical trials are research studies with human volunteers to see how new medicines or treatments work in people. Through clinical trials, researchers find new and better ways to prevent, detect, diagnose, control and treat illness and improve health.

Carefully conducted clinical trials are the safest and fastest way to find treatments that work. If you take aspirin to reduce your risk of a heart attack, or have ever received a flu or tetanus shot, or been immunized against diseases such as measles, mumps, rubella, you've benefited from clinical trials.

More than 60% of U.S. children with cancer participate in clinical trials. Consequently, there have been enormous improvements in treating childhood cancers. In the mid-1970s, about 55% of children with cancer were alive five years after diagnosis. In 2000, this figure had increased to 70%. In contrast, an estimated 3% to 5% of adult cancer patients participate in clinical trials, far fewer than is needed to answer the most critical questions about cancer quickly (Source: National Cancer Institute).

The effective cancer treatments of today are the result of progress made and knowledge learned from past clinical trials. Accordingly, people treated for cancer today are living longer. The more people that participate in clinical trials, the faster critical research questions can be answered.

Additionally, the more diverse the participant pool, the more confidence we have of the results and their benefits for all people. For many reasons, certain groups participate less on clinical trials than others. Groups often under-represented on cancer clinical trials include racial and ethnic minorities and women.


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Since the early 1970s, incidence rates for non-Hodgkin’s lymphoma have nearly doubled. Improved diagnosis has contributed greatly to the increase as doctors better understand cancer of lymphocytes and can distinguish it from other diseases.

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