New Chemo Effective For Unresponsive non-Hodgkin's Lymphoma

A new combination of five chemotherapy drugs was tested as safe and effective for patients with poor prognostic refractory (unresponsive) or multiple disease recurrent aggressive non-Hodgkin's lymphoma (NHL), according to the results of a phase II trial.

"CIBO-P (lomustine, ifosfamide, bleomycin, vincristine, and cisplatin) is a novel salvage regimen for patients with aggressive NHL," says Dr. Antonino Musolino from University Hospital of Parma, Italy. "It has clinically significant activity with a favorable toxicity profile in primary refractory disease and patients treated at second or subsequent relapses."

The results were published in May 15th issue of the journal Cancer (Cancer 2005;103:2109-2117).

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