Conflicting Information on Rheumatoid Arthritis

Submitted by mike Wed 03/01/2006

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In previous blog entries in October, November, and December 2004, I linked to articles about Remicade, Methotrexate, and Humira respectively. Article, studies, even a manufacturer stated that certain rheumatoid arthritis (RA)medications could be linked to increased lymphoma risk.

Today, articles seem to change the story - in that famous (??) journal Arthritis & Rheumatism, Swedish researchers say that having longstanding RA makes one 70 times more at risk for contracting lymphoma.

The researchers also looked for an association between lymphoma risk and RA treatment, including methotrexate, anti-malarial agents, oral steroids, non-steroidal anti-inflammatory drugs, and aspirin. But no link association was found.

So what is the story? As usual, talk to your doctor to interpret the rocky road - they are educated to look at your situation and advise you best.

Baecklund E et al. Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis. Arthritis & Rheumatism. 2006; 54(3):692-701.

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