ACOG Presentation: Chemotherapy Can Be Given in 2nd and 3rd Trimester to Pregnant Women With Lymphoma

According to new research presented at the 54th Annual Clinical Meeting of the American College of Obstetricians and Gynecologists (ACOG), some diagnoses of lymphoma can be safely treated during pregnancy, and chemotherapy in the second and third trimester appears to be relatively safe to the fetus.

The study by Elyce Cardonick, MD, of Cooper University Hospital, showed of the 22 women with lymphoma, 2 received chemotherapy post partum and 20 received it in the second and third trimester. All 22 women delivered live-born infants, a mean of 5 weeks early. Some of the women had induced labors so they could remain on chemotherapy. Mean birth weight was 2.5 kg (5.5 lbs).

"There's no need to terminate pregnancy in women with lymphoma, as chemotherapy can be given in the second and third trimester," said Dr. Cardonick. "Lymphoma can be safely diagnosed and treated during pregnancy, and chemotherapy in the second and third trimester appears safe. Pregnant women given different regimens or lower doses of chemotherapy because of the pregnancy may be at risk for recurrence, however." DG dispatch

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