Study on AIDS-Related Lymphomas

Submitted by mike Fri 07/08/2005

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A recent article published in the Journal of Clinical Oncology reports that survivals of patients diagnosed with AIDS-related diffuse large cell lymphoma (DLCL) have improved with recent advances in the use of highly active anti-retroviral therapy (HAART). However, similarly treated patients diagnosed with AIDS-related Burkitt’s Lymphoma have not experienced the same benefits.

AIDS-related lymphomas are often aggressive and grow and spread quickly. The three types of AIDS-related lymphomas include: diffuse large B-cell lymphoma, B-cell immunoblastic lymphoma and small non-cleaved cell lymphoma, which is also known as Burkitt’s lymphoma (HIV-BL). Each type is defined by the characteristics of the cell observed under a microscope. Prior to the development of HAART patients with AIDS-related lymphomas had a very poor prognosis. However, following routine HAART more aggressive chemotherapy has led to survivals approaching those observed in non-AIDS related lymphomas.

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