Velcade Side Effects


Velcade (bortezomib) is an anti-cancer drug treatment administered by IV. It is indicated for the treatment of two diseases: multiple myeloma and mantle cell lymphoma. It was first approved by the US Food & Drug Administration in 2003. In this entry we're citing the most commonly reported side effects of Velcade along with side effects of Velcade considered serious enough that they demand medical attention.

Common Side Effects of Velcade

The following side effects are considered to be common side effects of taking Velcade. This shouldn't be taken to mean that every person receiving the treatment will experience any or all of these side effects. Some will experience none; others, perhaps more than their share.

  • Joint pain
  • Bone pain
  • Muscle pain
  • Constipation or diarrhea
  • Nausea or stomach upset
  • Feeling tired
  • Insomnia or interrupted sleep
  • Dizziness, lightheadedness, headache
  • Appetite loss

Serious Side Effects of Velcade

The following serious side effects might occur as a result of receiving Velcade. If they do, one should seek immediate medical attention:

  • Severe allergic reactions (this could include a rash, itching, hives, problems breathing, chest tightness, swelling of the mouth, face, lips, or tongue)
  • Vision changes (blurred or loss of vision)
  • Peripheral neuropathy (burning, numb pain in hands or feet)
  • Chest pain, shortness of breath
  • Persistent diarrhea or constipation
  • Vomiting or stomach pain
  • Signs of infection including cough, chills, fever, sore throat
  • Sluggishness or slurred speech
  • Persistent muscle pain, cramping, or weakness
  • Urine changes (in amount or change to dark-colored urine)
  • Rapid or irregular heartbeat
  • Changes in mood
  • Suicidal thoughts
  • Fainting, confusion, seizure
  • Persistent headache
  • Sudden weight gain
  • Swelling and / or pain in the feet, ankles, legs
  • Yellowing of the skin or the eyes

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