Ifosfamide Side Effects


Ifosfamide is an anti-cancer chemotherapy drug that was first approved by the US Food and Drug Administration in 1988. It is indicated for the treatment of some testicular cancers and some cervical cancers.

Because ifosfamide is so molecularly similar to one of the oldest and most well-understood chemotherapeutics—cyclophosphamide—it has uses against a broad number of different cancers, including brain tumors as well as breast and lung cancers, to name just a few.

The role of ifosfamide in lymphoma treatment is most notable in its use in the combination chemotherapy regimen known as ICE—a preparative regimen for bone marrow transplantations.

Common Side Effects of Ifosfamide

The following side effects are considered to be common side effects of taking Ifosfamide. This list is not inclusive of all side effects, and no patient should expect to experience all of them.

  • Nausea
  • Vomiting
  • Appetite loss
  • Diarrhea
  • Hair loss (temporary)

Serious Side Effects of Ifosfamide

The following serious side effects may occur after receiving any treatment including ifosfamide. If any of these side effects occur, one should seek immediate medical attention:

  • Allergic reactions (this could include a rash, itching, hives, problems breathing, chest tightness, swelling of the mouth, face, lips, or tongue)
  • Frequent, painful or difficult urination
  • Blood in one's urine
  • Stool that is black or tarry in appearance
  • Signs of infection including cough, chills, fever, sore throat
  • Sluggishness, sleepiness, confusion, or hallucinations
  • Unusual bleeding or bruising

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