Diagnosis and Staging of Large Cell Lymphoma

Large Cell Lymphoma (LCL) is typically an aggressive (fast growing) cancer of either the B cell or T cell type. They are one of the most common types of lymphoma, accounting for 31% of all non-Hodgkin’s diagnoses. Approximately 79% of cases are B-cell cancers, 16% are T-cell cancers, and the remaining 5% come from an unidentifiable origin. These diseases often affect the elderly population, but they can also affect children.

Call

Large Cell Lymphomas are grouped and classified together because of similarities in the cell mutations and markers. They also present with the same types of symptoms such as fatigue, weakness, weight loss, night sweats, and swollen lymph nodes.

Since these cancers are typically aggressive, they can spread to many different areas in the body. Tumors may develop either in the lymph nodes or other lymph tissue and then spread to the bone, central nervous system, liver, lungs, spleen, testes, thyroid, or gastrointestinal tract.

Diagnosis and Staging of Large Cell Lymphoma

Diagnosis and staging differs slightly for each subtype of LCL. However, blood work, bone marrow biopsies, X-rays, CT scans, PET scans, and ultrasounds may be used for diagnosis and staging in all cases. Staging depends on the location and spread of the disease, with the lower stages typically contained in one area of the lymph nodes and the later stages marked by spread throughout the body.

For more information on large cell lymphomas see the following:

Photo: Pexels

Call

More Articles

More Articles

This entry looks at Non Hodgkin's Lymphoma in the lungs, clinically known as pulmonary lymphoma, one of the subtypes of lymphoma. 'Lymphoma' is an...

In order to prevent developing any subtype of lymphoma, it would be helpful to know the causes of lymphoma. Unfortunately, in virtually every case...

BEAM chemotherapy is an acronym representing a small family of combination chemotherapy regimens that are used chiefly as salvage regimens in the...

There are two types of cancer: benign and malignant. Benign cancers are the kind that don't spread and don't threaten one's life. Malignant...

The Erythrocyte Sedimentation Rate (ESR - sometimes called sed rate or sedimentation rate) is a nonspecific screening test for various...

Blood counts can be used to identify disease and monitor patient health during cancer treatments. Though these tests cannot diagnose lymphoma on...

MALT lymphoma is a rare B-cell non-Hodgkin's lymphoma that typically runs an indolent or slow-growing clinical...

Mantle cell lymphoma (MCL) is just one of 50-60 known B-cell subtypes of...

After some of the dust has settled, the thoughts of many new lymphoma patients turn to diet and nutrition. They want to know if, in the past,...

According to a study by Japanese researchers, the SMILE combination chemotherapy protocol is effective against extranodal natural killer/T-cell...

In a perfect world, every case of cancer would respond to, and be cured by first-line therapy. Unfortunately, it is not often the case. This is...

Patients treated with maintenance rituximab had three times longer progression-free survival. This is a summary of an article published in the...

Prednisone is a glucocorticosteroid (a steroid) used in the treatment of many types of cancers. It functions as an anti-inflammatory medicine that...

In 1964, researchers at the National Cancer Institute developed the first combination chemotherapy that cured a...

Since so many chemotherapy agents can affect a patient’s sex drive and fertility, thinking about these issues prior...