Gazyva Approved By FDA for Follicular Lymphoma

The Food and Drug Administration has approved Gazyva plus bendamustine for the treatment of follicular lymphoma.

The approval is relevant to patients who have relapsed after or are unresponsive to the drug Rituxan, according to Gazyva's manufacturer Genentech.

"People with follicular lymphoma whose disease returns or worsens despite treatment with a Rituxan-containing regimen need more options because the disease becomes more difficult to treat each time it comes back," said Sandra Horning, Genentech's chief medical officer and head of Global Product Development.

In trials, researchers found that Gazyva plus bendamustine - followed by Gazyva alone - slowed disease progression by 52 percent compared with patients taking a Rituxan regimen or just bendamustine alone.

Follicular lymphoma treatment options

Follicular lymphoma (FL) is the most common type of non-Hodgkin lymphoma, and many people have no symptoms at the time they are diagnosed.

According to the Lymphoma Research Foundation, FL is generally responsive to radiation and chemotherapy, and rituximab and bendamustine are the most common drugs used to treat the condition.

Because the disease often returns, however, Gazyva's promise may represent hope for patients who aren't responsive to the more traditional treatment methods for FL.

"Gazyva plus bendamustine provides a new treatment option that can be used after relapse to significantly reduce the risk of progression or death," Horning said.

Source: CURE Today

Image courtesy of everydayplus/FreeDigitalPhotos.net

More Articles

More Articles

Mantle cell lymphoma (MCL) is a rare type of B-Cell lymphoma. It presents itself in the mantle zone of lymph nodes...

Large Cell Lymphoma (LCL) is typically an aggressive (fast growing) cancer of either the B cell or T cell type. They are one of the most common...

Indolent Lymphoma, or Indolent Non-Hodgkin’s Lymphomas (NHLs), are slow growing, low-grade cancers (as opposed to ...

A lymphoma prognosis varies greatly depending on the type of lymphoma. There are more than 35 types of lymphoma, including 5 types of...

Lymphomas are classified based on the type of cells involved. Non-Hodgkin’s lymphomas are marked by mutations of...

Hodgkin's Lymphoma (Disease) has a colorful history: It was not the first cancer discovered but it was one of the first in which treatments were...

There are two types of cancer: benign and malignant. Benign cancers are the kind that don't spread and don't threaten one's life. Malignant...

Cancer bracelets are undeniably popular, and if purchased through reliable sources such as major charities, they help contribute to the fight...

Hodgkin's Disease—also referred to as Hodgkin's Lymphoma, these are the exact same diseases, just...

Lymphoma is a cancer of the b- and t-cell lymphocytes, part of the immune system. They account for the most frequent head and neck malignancies....

Lymphoma is a cancer of the lymphatic system, causing B-cell or...

Lymphoma is a cancer affecting the white blood cells (lymphocytes) of the body's immune system. The cells begin to grow abnormally and much faster...

As a kind of cancer, lymphoma attacks the lymphocytes and lymph nodes that are part of the immune system. Head and neck lymphoma results when...

Some cancers have clear environmental causes. Oral cancer is strongly tied to the use of chewing tobacco, and lung cancer is well-known to be much...

The Follicular Lymphoma International Prognostic Index, or FLIPI, is a standardized guide to help oncological diagnosticians accurately calculate...