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I am a 60-years-old female. I suffered from Non-Hodgkin's Lymphoma 10 years ago. After several chemotherapy I received BMT from my syster 4 years ago. After BMT my condition has been stable. But it recurred this year. What treatment is left for me now?

Submitted by itoty on Fri 03/05/2010 - 05:56
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Submitted by Susan K. Walker on Sat, 03/06/2010 - 08:21.

I believe that the medical industry has made great progress with NHL from ten years ago and I have great optimism in the future for NHL patients. My doctor ( I have NHL) claims the progress just within the last two years is astounding.

The only treatments that I am aware of that are approved by the FDA and safe and effective are the standard R-CHOP, (Rituximab) administered in six rounds in either one week or two week increments. Another therapy is radioimmunotherapy called "Zevalin" which I am undergoing next week for maintenance. It is a relatively new drug that was just approved by the FDA for a broader use in fighting cancer. It is shown by some studies to keep NHL at bay longer than standard Rixutimab. There is not enough data (only some group studies) to prove this to be true.

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Submitted by itoty on Sun, 03/07/2010 - 06:07.

Thank you very much for your kind answer. I hope I can get better by the new treatment. itoty

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Submitted by karenfaust54 on Sat, 03/27/2010 - 20:26.

Susan: How did your treatment go and what is the prognosis?
My hubands NHL came back and they want to do the same treatment on him eventually. Right now they are restarting the Rituximab which only gave him three months remission. The cancer returned with a vengence. Please let me know how your doing.

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Submitted by Ross on Sun, 03/07/2010 - 11:56.

There are two items you might want to consider. The first regards a medication called Bexxar and the other concerns a less toxic chemo regimen than RCHOP, Treanda plus Rituxan.

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Submitted by itoty on Sun, 03/07/2010 - 18:40.

Thank you for your comment. I've never heard of Bexxar I'll check it up. itoty

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Submitted by itoty on Sun, 03/07/2010 - 18:44.

Has anybody ever received an effective treatment after the recuurence after BMT and survived? I am despearte to know the most effective treament after BMT.

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Submitted by CloweG on Sun, 03/21/2010 - 22:09.

Radioimmunotherapy is a form of biologic therapy that combines a protein that attaches to the target cell with a small dose of radioactive material that disrupts and kills the cell. Unique proteins called antigens exist on the surface of every cell. The body monitors these proteins, and when it recognizes a cell as foreign or defective, it creates other antigen-specific proteins called antibodies to attach to the unwanted cells and disable them. With NHL, this system of protection fails and defective cancerous cells are allowed to continue growing. Zevalin is radioactive when it is being administered, and care should be taken to minimize exposure of patients and health care providers. And if you’re not satisfied with the answers, there are still many advice columns and advice columnists you can run to. Just don’t lose hope and believe in God.

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Since the early 1970s, incidence rates for non-Hodgkin’s lymphoma have nearly doubled. Improved diagnosis has contributed greatly to the increase as doctors better understand cancer of lymphocytes and can distinguish it from other diseases.