Can FNHL stage 4 be passed on to an unborn child. I was thinking of becoming a surogate for a close friend, but do not want to take a chance of passing this on to their baby.

Stephanie- To my knowledge,

Stephanie-
To my knowledge, fewer than 30 cases of a cancer passing from mother to child in the womb have been published in the medical literature. Assuming many aren't, this still makes the likelihood extraordinarily, amazingly, unlikely

But, apparently, not impossible. While the placenta is supposed to provide the barrier, and while the child's own immune system is supposed to kill any cancerous cells that might sneak across the the placenta, in a handful of proven cases, the system failed. From what I can tell, the cancers are generally of the blood kind-- leukemias and lymphomas. The cells cross the barrier and begin to grow in the child.

Again, it's really rare, and I don't think anyone can tell you specifically about FNHL, but it can and does happen.

FYI, here's the most recent paper on the subject, Immunologically silent cancer clone transmission from mother to offspring from the Proceedings of the National Academy of Sciences.

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