WHO Classification System
Over the years, various classification systems have been used to differentiate lymphomas including the Rappaport Classification (used until the 70's), the Working Formulation, the National Cancer Institute Working Formulation, and the Revised European-American Lymphoma Classification (REAL).
We have chosen to present the World Health Organization's International Classification of Diseases (WHO ICD).
The WHO classification has its origins in the 1850s. The first edition, known as the International List of Causes of Death, was adopted by the International Statistical Institute in 1893. The ICD is the international standard diagnostic classification. It is used to classify diseases and other health problems recorded on many types of health and vital records including death certificates and health records. These records also provide the basis for the compilation of national mortality and morbidity statistics by WHO Member States.
The older Rappaport, Working Formulation, and REAL categories are described in a separate section for reference. This might be helpful if a patient's records state some of the older lymphoma classifications.
- Lymphocytic-histiocytic predominance
- Nodular sclerosis
- Mixed cellularity
- Lymphocytic depletion
- Other Hodgkin's disease
- Hodgkin's disease, unspecified
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- Small cleaved cell, follicular
- Mixed small cleaved and large cell, follicular
- Large cell, follicular
- Other types of follicular non-Hodgkin's lymphoma
- Follicular non-Hodgkin's lymphoma, unspecified
- Nodular non-Hodgkin's lymphoma NOS
